New Biosensor Can Detect Biomarkers Associated with TBI

Mar 7, 2022

Brooks Schuelke, Esq.
Schuelke Law PLLC

Austin, TX (Law Firm Newswire) March 7, 2022 – Traumatic brain injury (TBI) is common in today’s world due to slips, trips, falls, sports, and serving in the military. Ongoing research has made giant strides in understanding it and helping to support it. 

The latest addition to the tools that can help detect changes in concentrations of chemicals in the body, sending the information to researchers in real-time is an infinitely small biosensor that detects biomarkers associated with TBI. This newest tool has been tested successfully in the Ohio State University lab.

The flexible chip biosensor is waterproof, thanks to a thin film of silicon dioxide, and thinner than human hair, which means it is minimally invasive for use in the brain. While these are initial results, and there is still a long way to go, the researchers are very encouraged that this could help people suffering from TBI.

After a head injury, secondary damage may happen that is detected by changes in potassium and sodium ion concentrations in the brain’s cerebrospinal fluid. The new chip in development would continually monitor the brain tissues to detect these changes and act as an early warning system that the TBI was taking a turn for the worse.

The chip has electronic components that sense a chemical of interest, produce a signal that can be detected and then analyzed outside the body. The chip is programmed to only respond to specific chemicals related to TBI. Testing indicates the chip could safely remain in a person’s body for a few years without harm. 

The focus of research now is to work more with the chemical sensing elements to extend the time they can function. Researchers also need to determine a body’s response to the chip over an extended period. The hope is this chip could be utilized for use with Alzheimer’s and Parkinson’s.

“Early and accurate intervention in a TBI case could improve the level of care and recovery time for a patient,” said Austin traumatic brain injury attorney Brooks Schuelke. “Since TBI is so prevalent in sports, and in the military, the chip, when fully functional, may make a huge difference to the lives of those living with a brain injury.” 

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